David is a Consultant in Anaesthesia and Intensive Care Medicine at University College London Hospitals NHS Foundation Trust. He is the Trust lead for Critical Care, Anaesthesia and Emergency Medicine Research.
His earlier research was the first to demonstrate mitochondrial dysfunction as a potential cause of sepsis induced organ failure in patients. He now leads a successful Critical Care clinical trials team which are recognised as one of the highest performing teams within the UK and capable of performing on a global level. They have run over 30 clinical trials, specialising in early phase interventions in areas such as sepsis and ARDS with global firsts, high recruitment rates and data quality. However, he feels the lack of progress in this area has been hampered by the diagnostic uncertainty that the clinician and researcher frequently face. He is co-applicant on several grant awards aimed at improving patient monitoring, detecting infection and the associated pathogen with significantly higher confidence and speed than is currently possible.
He also co-leads one of the most exciting health care data projects in the UK, the Health Informatic Collaborative. This project aims to create an IT capability with an unparalleled level of detail, capable of answering complex clinical and research questions.