Professor Mike Clarke has more than 30 years’ experience in rigorous assessments of the effects of health and social care in a wide range of areas. He has worked on many randomised trials and systematic reviews in a wide variety of topic areas and has an international reputation in the design and conduct of trials and evidence synthesis, including the evaluation of the methods for this research. He is Director of the Northern Ireland Clinical Trials Unit, Director of the Northern Ireland Methodology Hub, and Co-ordinating Editor of the Cochrane Methodology Review Group. Mike teaches widely about trials and reviews and is actively involved in a variety of knowledge transfer projects, including being Podcast Editor for Cochrane Reviews and helping to produce the more than 650 podcasts released to date. In 2004, he was one of the founders of Evidence Aid, which is improving access to research for disasters and humanitarian emergencies. He is now its emeritus Research Director and has overseen the production of hundreds of summaries for more than 1000 systematic reviews relevant to health emergencies and disaster risk management, including more than 500 summaries for COVID-19.