Paul originally studied undergraduate physics and then medicine. Graduating from The Manchester Medical School 1989, he went on to study clinical academic surgery, emergency medicine and critical care at the Universities of Glasgow and Manchester in the UK, and at the Catholic University of Leuven, Belgium.

As MRC PhD Clinical Training Fellow, supervised by Professor Rod Little, he developed non-invasive methods to transduce and study dynamic cardio-respiratory responses to tissue injury and haemorrhage.

He was appointed to his current clinical academic post at the University of Manchester in 2003, developing clinical services and academic practice in Critical Care Medicine at the Northern Care Alliance NHS Foundation Trust (Salford Care Organisation). He developed and provides leadership for a programme of work, funded largely by the National Institute of Health Research (NIHR), investigating the clinical utility of emerging molecular diagnostic technologies in the setting of sterile tissue injury and severe infection. Funded by Innovate UK (formerly Technology Strategy Board) he also leads a programme of work developing novel technologies aimed at rapid point-of-care infection/sepsis diagnosis.

Paul was appointed NIHR Clinical Research Network’s National Deputy Medical Director in 2022. He provides strategic leadership for the development and delivery of a large portfolio of national clinical research in NHS acute hospital settings and he represents NIHR internationally. As a former NIHR National Specialty Lead for Critical Care, he served on NIHR’s Urgent Public Health Research Advisory Group, providing expert advice on research priority for DHSC and UK’s CMOs during the COVID-19 pandemic. In addition, he is Research Professor at the Humanitarian and Conflict Response Institute, providing strategic interdisciplinary leadership in health and social justice.